Which of the following is a symptom of stimulant use?

Reduced appetite is a common symptom associated with the use of stimulants. Stimulants, such as amphetamines and cocaine, can increase energy levels and alertness, often leading to a decrease in hunger. This effect is due to the way these substances influence neurotransmitters in the brain, particularly those related to mood and reward pathways, which can suppress appetite while simultaneously boosting energy.

The other options present symptoms associated with different conditions or substance use. For instance, profound depression and long periods of sleep are more commonly linked with depressants or certain mental health conditions rather than the stimulating effects of stimulants. Agitation can occur with stimulant use, but reduced appetite is a more direct and widely recognized symptom specific to stimulants.